Chen is also leading a project which involves sifting through a large library of different chemical compounds to see if any can make beta cells more resilient to viral attack. So far they have already identified one particular compound called trans-ISRIB, which appears to be capable of protecting the insulin-producing capacities of beta cells when infected with Sars-CoV-2 in a petri dish. While this is not yet approved by regulators nor tested in humans, and so cannot be used in Covid-19 patients experiencing blood sugar abnormalities at the moment, Chen hopes that in future it could be administered as a preventative drug for vulnerable individuals in the aftermath of infection.
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